This "Men into Space" board game allowed players to play a turn-based game inspired by the television program, which aired during the 1959–60 season. Up to four players could move colored "space cones" around the board according to the instructions on 24 cardboard cards, which also included "Did You Know" space facts on the reverse.

In its one season of half hour black and white programs, "Men into Space" depicted the realistic adventures of Colonel Edward McCauley, head of a fictional American space program. Aimed at adults, executed with the cooperation of the Department of Defense, and aired on CBS, "Men into Space" offered a fact-based depiction of space flight in the near future of the budding space age. It was produced by Ziv Television Programs, Inc., a Midwestern company known as the leading producer of first-run syndicated programming.

John C. Fredriksen, who is also the author of an eponymous episode guide to Men into Space, gave the board game to the Smithsonian National Air and Space Museum in 2013.